笔贰厂罢含核蛋白抗体
规格：1尘驳/1尘濒
英文名： PCNP
别名： PCNP; PCNP_HUMAN; PEST containing nuclear protein; PEST proteolytic signal containing nuclear protein; PEST proteolytic signal-containing nuclear protein; PEST-containing nuclear protein.
分子量： 19kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PCNP
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
笔贰厂罢含核蛋白抗体产物介绍：background: PCNP is a novel 178 amino acid nuclear protein implied to play a role in cell cycle regulation and tumorigenesis. PCNP is ubiquitinated post-translationally by NIRF (Np95/ICBP90-like RING finger protein), a ubiquitin ligase. Existing as three isoforms produced by alternative splicing events, PCNP is encoded by a gene mapping to human chromosome 3q12.3. Chromosome 3 houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease 笔贰厂罢含核蛋白抗体are a few of the numerous genetic diseases associated with chromosome 3 Function: May be involved in cell cycle regulation. Subunit: Interacts with UHRF2/NIRF. Post-translational modifications: Ubiquitinated; mediated by UHRF2 and leading to its subsequent proteasomal degradation. Database links: Entrez Gene: 57092 Human Entrez Gene: 76302 Mouse Entrez Gene: 288165 Rat SwissProt: Q8WW12 笔贰厂罢含核蛋白抗体Human SwissProt: Q6P8I4 Mouse SwissProt: Q7TP40 Rat Unigene: 275865 Human Unigene: 202642 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
笔贰厂罢含核蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 染色质和核信号 细胞周期蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid