细胞周期依赖性激酶抑制相关蛋白抗体
规格：1尘驳/1尘濒
英文名： P15RS
别名： Cyclin dependent kinase 2B inhibitor related protein; Cyclin dependent kinase inhibitor 2B related protein (p15INK4B related protein); Cyclin dependent kinase inhibitor 2B related protein; Cyclin depe
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RPRD1A/P
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse,
细胞定位：
细胞周期依赖性激酶抑制相关蛋白抗体产物介绍：background: P15RS is upregulated in cells overexpressing cyclin-dependent kinase inhibitor p15(INK4b) (CDKN2B; MIM 600431) and may have a role in cell cycle regulation Function: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle. Subunit: Associates with the RNA 细胞周期依赖性激酶抑制相关蛋白抗体polymerase II complex. Similarity: Belongs to the UPF0400 (RTT103) family. Contains 1 CID domain. Gene ID: 55197 Database links: Entrez Gene: 420953 Chicken Entrez Gene: 504355 Cow Entrez Gene: 55197 Human Entrez Gene: 225283 Mouse Omim: 610347 Human SwissProt: Q5ZM30 Chicken SwissProt: Q0P5J9 Cow SwissProt: Q96P16 Human SwissProt: Q8VDS4 Mouse细胞周期依赖性激酶抑制相关蛋白抗体 Unigene: 464912 Human Unigene: 28427 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞周期依赖性激酶抑制相关蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 激酶和磷酸酶 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid