双微体2癌基因结合蛋白抗体
规格：1尘驳/1尘濒
英文名： MDM2BP
别名： MDM 2 binding protein; MDM 2 BP; MDM2 (mouse double minute 2) binding protein 104kD; MDM2 (mouse double minute 2) binding protein; MDM2 binding protein; MDM2 BP; Mdm2 transformed 3T3 cell double minut
分子量： 102kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MTBP/MDM
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
细胞定位：
双微体2癌基因结合蛋白抗体产物介绍：background: This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. Function: Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination 双微体2癌基因结合蛋白抗体of p53/TP53 and its subsequent degradation. Subunit: Interacts with MDM2. Similarity: Belongs to the MTBP family. Database links: Entrez Gene: 27085 Human Entrez Gene: 105837 Mouse Omim: 605927 Human SwissProt: Q96DY7 Human双微体2癌基因结合蛋白抗体 SwissProt: Q80VU3 Mouse SwissProt: Q8BJS8 Mouse SwissProt: Q8BTU9 Mouse SwissProt: Q8BTW0 Mouse SwissProt: Q9ER61 Mouse Unigene: 186433 Human Unigene: 46701 Human Unigene: 61901 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
双微体2癌基因结合蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 染色质和核信号 细胞周期蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid