骨碱性磷酸酶抗体
规格：1尘驳/1尘濒
英文名： Bone Alkaline Phosphatase
别名： tissue-nonspecific isozyme; AKP2; Alkaline phosphatase; Alkaline phosphatase liver/bone/kidney isozyme; Alpl; AP-TNAP; HOPS; Liver/bone/kidney isozyme; PHOA; PPBT_HUMAN; Tissue non specific alkaline p
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Bone Alk
交叉反应：Human, Mouse, Rat, Cow, Rabbit,
细胞定位：细胞膜
骨碱性磷酸酶抗体产物介绍：background: Defects in ALPL are a cause of hypophosphatasia (HOPS) . HOPS is an inherited metabolic bone disease characterized by defective skeletal mineralization. Four hypophosphatasia forms are distinguished, depending on the age of onset: perinatal, infantile, childhood and type. The perinatal form is the most severe and is almost always fatal. Patients with only premature loss of deciduous teeth, but with no bone disease are regarded as having odontohypophosphatasia. Function: This isozyme may play a role in skeletal mineralization. Subunit: Homodimer. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Post-translational modifications: Glycosylated. DISEASE: Defects in ALPL are a cause of hypophosphatasia (HOPS) [MIM:146300]. HOPS is an inherited metabolic bone disease characterized by defective skeletal mineralization. Four hypophosphatasia forms are distinguished, depending on the age of onset: perinatal, infantile, 骨碱性磷酸酶抗体childhood and type. The perinatal form is the most severe and is almost always fatal. Patients with only premature loss of deciduous teeth, but with no bone disease are regarded as having odontohypophosphatasia (odonto). Defects in ALPL are a cause of hypophosphatasia childhood type (HOPSC) [MIM:241510]. Defects in ALPL are a cause of hypophosphatasia infantile type (HOPSI) [MIM:241500]. Similarity: Belongs to the alkaline phosphatase family. Gene ID: 249 Database links: Entrez Gene: 249 Human Entrez Gene: 11647 Mouse Entrez Gene: 25586 Rat 骨碱性磷酸酶抗体Omim: 171760 Human SwissProt: P05186 Human SwissProt: P09242 Mouse SwissProt: P08289 Rat Unigene: 75431 Human Unigene: 288186 Mouse Unigene: 82764 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产骨碱性磷酸酶抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 干细胞 激酶和磷酸酶 细胞骨架 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid