神经元，肌肉特异性烯醇化酶抗体
规格：1尘驳/1尘濒
英文名： ENO1+ENO2+ENO3
别名： ENO1 + ENO2 + ENO3; 2-phospho-D-glycerate hydro-lyase; Alpha-enolase; Beta-enolase; C-myc promoter-binding protein; Crystallin Tau, included; ENO1L1; Enolase 1, (alpha); Enolase 2 (gamma, neuronal); E
分子量： 48kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ENO1+ENO
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse,
细胞定位：
神经元，肌肉特异性烯醇化酶抗体产物介绍：background: Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor. Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival. Enolase 3 appears to have a function in 神经元，肌肉特异性烯醇化酶抗体striated muscle development and regeneration. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter神经元，肌肉特异性烯醇化酶抗体 isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011].
产神经元，肌肉特异性烯醇化酶抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 染色质和核信号 信号转导 转录调节因子 激酶和磷酸酶 肿瘤细胞生物标志物 新陈代谢 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid