上皮细胞膜蛋白2抗体
规格:1尘驳/1尘濒
英文名: EMP2
别名: EMP-2; EMP2; EMP2_HUMAN; Epithelial membrane protein 2; Protein XMP.
分子量: 19/24kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human EMP2
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞膜
上皮细胞膜蛋白2抗体产物介绍:background: EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while上皮细胞膜蛋白2抗体 fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial 上皮细胞膜蛋白2抗体adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the PMP-22/EMP/MP20 family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产上皮细胞膜蛋白2抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 发育生物学 信号转导 激酶和磷酸酶 细胞粘附分子 细胞骨架
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid