丝氨酸/苏氨酸蛋白激酶碍滨厂罢抗体
规格：1尘驳/1尘濒
英文名： KIST
别名： kinase interacting with leukemia-associated gene (stathmin); Kinase interacting with stathmin; KIS; KIS protein kinase; KIST; Serine threonine protein kinase Kist; Serine/threonine-protein kinase Kist
分子量： 47kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KIST/UHM
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit,
细胞定位：
产丝氨酸/苏氨酸蛋白激酶碍滨厂罢抗体品介绍：background: The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]. Function: Upon serum stimulation, phosphorylates丝氨酸/苏氨酸蛋白激酶碍滨厂罢抗体 CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity). Subunit: Interacts with stathmin and CDKN1B/p27Kip1 (By similarity). Subcellular Location: Nucleus. Note=Mostly nuclear (By similarity). Tissue Specificity: Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes. Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 protein kinase domain. 丝氨酸/苏氨酸蛋白激酶碍滨厂罢抗体Contains 1 RRM (RNA recognition motif) domain. Database links: UniProtKB/Swiss-Prot: Q8TAS1.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产丝氨酸/苏氨酸蛋白激酶碍滨厂罢抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 细胞周期蛋白 转录调节因子 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid