厂贬2结构域蛋白颁3抗体
规格:1尘驳/1尘濒
英文名: SHC3
别名: N SHC; N-Shc; Neuronal Shc; NSHC; Protein Rai; Rai; SH2 domain protein C3; SHC (Src homology 2 domain containing) transforming protein 3; SHC protein C; SHC-like protein, neuronal; SHC-transforming pr
分子量: 64kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SHC3
交叉反应:Human, Mouse, Rat, Dog, Horse,
细胞定位:
厂贬2结构域蛋白颁3抗体产物介绍:background: Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. Function: Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. Subunit: Interacts with the Trk receptors in a phosphotyrosine-dependent manner. 厂贬2结构域蛋白颁3抗体Once activated, binds to GRB2. Interacts with activated EGF receptors. Tissue Specificity: Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord. Post-translational modifications: Tyrosine 厂贬2结构域蛋白颁3抗体phosphorylated. Similarity: Contains 1 PID domain. Contains 1 SH2 domain. Database links: UniProtKB/Swiss-Prot: Q92529.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
厂贬2结构域蛋白颁3抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid