细胞表面糖蛋白罢谤辞辫2抗体
规格：1尘驳/1尘濒
英文名： TROP2
别名： Cell surface glycoprotein Trop 2; Cell surface glycoprotein Trop-2; Cell surface glycoprotein Trop2; Epithelial glycoprotein 1; GA733 1; GA7331; M1S 1; M1S1; Membrane component chromosome 1 surface ma
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TROP2/TA
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞膜
细胞表面糖蛋白罢谤辞辫2抗体产物介绍：background: This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009] Function: May function as a growth factor receptor. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Placenta, pancreatic carcinoma cell lines. Post-translational modifications: The N-terminus is blocked. DISEASE: Corneal dystrophy, gelatinous drop-like (GDLD) [MIM:204870]: A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal细胞表面糖蛋白罢谤辞辫2抗体 amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the EPCAM family. Contains 1 thyroglobulin type-1细胞表面糖蛋白罢谤辞辫2抗体 domain. Database links: Entrez Gene: 4070 Human Entrez Gene: 56753 Mouse Entrez Gene: 494343 Rat Omim: 137290 Human SwissProt: P09758 Human SwissProt: Q8BGV3 Mouse SwissProt: Q6P9Z6 Rat Unigene: 23582 Human Unigene: 439913 Mouse Unigene: 24809 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞表面糖蛋白罢谤辞辫2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 肿瘤细胞生物标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid