搁补蝉样蛋白叠抗体
规格:1尘驳/1尘濒
英文名: RALB
别名: dRalb; GTP binding protein; RAS like protein B; Ras-related protein Ral-B; v ral simian leukemia viral oncogene homolog B (ras related GTP binding protein); v ral simian leukemia viral oncogene homolo
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RALB
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞浆 细胞膜
搁补蝉样蛋白叠抗体产物介绍:background: This gene encodes a GTP-binding protein that belongs to the small GTPase superfamily and Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. Function: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis. Subunit: Interacts with EXOC2 and EXOC8. Interacts搁补蝉样蛋白叠抗体 with RALBP1 via its effector domain. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side. Note=During late cytokinesis localizes at the midbody. Post-translational modifications: Prenylation is essential for membrane localization. The geranylgeranylated form and the farnesylated mutant does not undergo alternative prenylation in response to geranylgeranyltransferase I inhibitors (GGTIs) and farnesyltransferase I inhibitors (FTIs). Similarity: Belongs to the small GTPase superfamily. Ras family. Database links: Entrez Gene: 5899 Human Entrez Gene: 64143搁补蝉样蛋白叠抗体 Mouse Entrez Gene: 116546 Rat Omim: 179551 Human SwissProt: P11234 Human SwissProt: Q9JIW9 Mouse SwissProt: P36860 Rat Unigene: 469820 Human Unigene: 27832 Mouse Unigene: 4586 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
搁补蝉样蛋白叠抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 染色质和核信号 信号转导 转录调节因子 G蛋白偶联受体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid