神经上皮细胞转化基因1抗体
规格：1尘驳/1尘濒
英文名： NET1
别名： mNET1; ARHGEF8; GLYT2; Guanine nucleotide regulatory protein oncogene; NET1A; Neuroepithelial cell transforming gene 1; p65 Net1 proto oncogene; Rho guanine nucleotide exchange factor GEF 8; ARHG8_HUM
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NET1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞核 细胞浆
神经上皮细胞转化基因1抗体产物介绍：background: This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. Function: Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic 神经上皮细胞转化基因1抗体stress-induced RHOB activity in breast cancer cells leading to their cell death. Subunit: Interacts with RHOA in its GTP- and GDP-bound states, and with CDC42 in its GTP-bound state. Interacts with the PDZ 1 domain of BAIAP1. Subcellular Location: Cytoplasm (By similarity). Nucleus Tissue Specificity: Widely expressed. Similarity: Contains 1 DH (DBL-homology) domain. Contains 1 PH domain. Database links: 神经上皮细胞转化基因1抗体 UniProtKB/Swiss-Prot: Q7Z628.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经上皮细胞转化基因1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 染色质和核信号 神经生物学 信号转导 转录调节因子 G蛋白偶联受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid