搁础厂相关抑细胞生长蛋白1抗体
规格:1尘驳/1尘濒
英文名: DIRAS1
别名: Di Ras1; DIRAS family GTP binding RAS like 1; Distinct subgroup of the Ras family member 1; GBTS1; GTP binding protein Di Ras1; Ras related inhibitor of cell growth; RIG; Rig protein; Small GTP bindin
分子量: 22kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DIRAS1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
细胞定位:细胞浆 细胞膜
搁础厂相关抑细胞生长蛋白1抗体产物介绍:background: The three human RAS genes encode highly related 188 to 189 amino acid proteins, designated H-Ras, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing). Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in搁础厂相关抑细胞生长蛋白1抗体 cancers, leading to increased invasion and metastasis, and decreased apoptosis. DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. It is highly expressed in heart and brain. Function: Displays low GTPase activity and exist predominantly in the GTP-bound form. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Tissue Specificity:搁础厂相关抑细胞生长蛋白1抗体 Highly expressed in heart and brain. Similarity: Belongs to the small GTPase superfamily. Di-Ras family. Database links: UniProtKB/Swiss-Prot: O95057.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
搁础厂相关抑细胞生长蛋白1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 转录调节因子 G蛋白偶联受体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid