组蛋白连接作用蛋白抗体
规格：1尘驳/1尘濒
英文名： SHPRH
别名： E3 ubiquitin-protein ligase SHPRH; histone-linker; PHD and RING finger domain-containing helicase; SNF2; SNF2 histone linker PHD RING helicase; SHPRH_HUMAN.
分子量： 193kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SHPRH
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：
组蛋白连接作用蛋白抗体产物介绍：background: SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 Function: E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin 组蛋白连接作用蛋白抗体chains linked through 'Lys-63'. Subunit: Homodimer. Interacts with HLTF, PCNA, UBE2N and RAD18. Tissue Specificity: Broadly expressed. Similarity: Belongs to the SNF2/RAD54 helicase family. Contains 1 H15 (linker histone H1/H5 globular) domain.组蛋白连接作用蛋白抗体 Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Contains 1 PHD-type zinc finger. Contains 1 RING-type zinc finger. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
组蛋白连接作用蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 细胞周期蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid