贵础惭21颁蛋白抗体
规格:1尘驳/1尘濒
英文名: FAM21C
别名: FA21C_HUMAN; FAM21A; FAM21C; Family with sequence similarity 21 member C; Hypothetical protein LOC253725; KIAA0592; Protein FAM21C; Vaccinia virus penetration factor; VPEF; WASH complex subunit FAM21C
分子量: 144kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FAM21C
交叉反应:贬耻尘补苍,
细胞定位:细胞浆
贵础惭21颁蛋白抗体产物介绍:background: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. In the complex, it probably mediates the recruitment of the complex to endosome membranes. Plays a role in fluid-phase endocytosis, a process exploited by vaccinia intracellular mature virus (IMV) to enter cells. As贵础惭21颁蛋白抗体 a result, may facilitate the penetration of IMV into cells. Subcellular Location: Early endosome membrane. Cell membrane. Partially colocalizes with RAB11A, a recycling endosome marker. Associates with lipid raft microdomains on the plasma membrane. Similarity:贵础惭21颁蛋白抗体 Belongs to the FAM21 family. Gene ID: 253725 Database links: Entrez Gene: 253725 Human SwissProt: Q9Y4E1 Human Unigene: 365286 Human Unigene: 449662 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
贵础惭21颁蛋白抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid