贵础惭173础蛋白抗体
规格:1尘驳/1尘濒
英文名: FAM173A
别名: C16orf24; F173A_HUMAN; Fam173a; Family with sequence similarity 173, member A; LA16c-444G9.1; MGC2494; Protein FAM173A.
分子量: 25kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FAM173A
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
贵础惭173础蛋白抗体产物介绍:background: FAM173A is a 235 amino acid single-pass membrane protein belonging to the FAM173 family and is encoded by a gene located on human chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. 贵础惭173础蛋白抗体The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene that encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.贵础惭173础蛋白抗体 An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. Subcellular Location: Membrane. Similarity: Belongs to the FAM173 family. Gene ID: 65990 Database links: Entrez Gene: 65990 Human SwissProt: Q9BQD7 Human Unigene: 166244 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
贵础惭173础蛋白抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid