贵础惭162础蛋白抗体
规格：1尘驳/1尘濒
英文名： FAM162A
别名： C3orf28; Chromosome 3 open reading frame 28; DC16; E2-induced gene 5 protein; E2IG5; F162A_HUMAN; Fam162a; Family with sequence similarity 162, member A1; Growth and transformation-dependent protein;
分子量： 17kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FAM162A
交叉反应：Human, Mouse, Rat, Pig, Horse,
细胞定位：细胞膜
贵础惭162础蛋白抗体产物介绍：background: HGTD-P (human growth and transformation-dependent protein), also known as E2IG5 or FAM162A, is a 154 amino acid single-pass membrane protein belonging to the UPF0389 family. Considered a proapoptotic protein, HGTD-P is an effector of cell death induced by hypoxia-ischemia (HI) and is therefore considered a potential target in treating HI-induced brain damage. HGTD-P localizes to the mitochondria and, when overexpressed, induces the mitochondrial permeability transition by interacting with voltage贵础惭162础蛋白抗体 dependent anion channels. HGTD-P facilitates apoptotic cell death via the mitochondrial apoptotic cascades, including permeability transition, cytochrome c release and caspase 9 activation. HGTD-P is regulated and activated by HIF-1?through a hypoxia-responsive贵础惭162础蛋白抗体 element on the HGTD-P promoter region. Subcellular Location: Membrane. Similarity: Belongs to the UPF0389 family. Gene ID: 26355 Database links: Entrez Gene: 26355 Human Omim: 608017 Human SwissProt: Q96A26 Human Unigene: 584881 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
贵础惭162础蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid