弹性蛋白微原纤维界面因子1抗体
规格：1尘驳/1尘濒
英文名： EMILIN1
别名： Elastin microfibril interface located protein 1; Elastin microfibril interface located protein; Elastin microfibril interface-located protein 1; Elastin microfibril interfacer 1; EMIL1_HUMAN; EMILIN 1
分子量： 104kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EMILIN1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞浆
弹性蛋白微原纤维界面因子1抗体产物介绍：background: This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung. [provided by RefSeq, Sep 2009] Function: May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity. Subunit: Homotrimer associated through a moderately stable interaction of the C-terminal globular C1q domains, allowing the nucleation of the triple helix and then a further quaternary assembly to higher-order polymers via intermolecular disulfide bonds. Interacts with EMILIN2.弹性蛋白微原纤维界面因子1抗体 Subcellular Location: Secreted; extracellular space; extracellular matrix. Found mainly at the interface between amorphous elastin and microfibrils. Tissue Specificity: Distributed in tissues where resilience and elastic recoil are prominent. Highest levels in the small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in liver, ovary, colon, stomach, lymph node and spleen; heart, bladder, prostate, adrenal gland, mammary gland, placenta and kidney showed low expression whereas a series of other tissues, including skeletal muscle and different regions of brain show no expression. DISEASE:弹性蛋白微原纤维界面因子1抗体 Distributed in tissues where resilience and elastic recoil are prominent. Highest levels in the small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in liver, ovary, colon, stomach, lymph node and spleen; heart, bladder, prostate, adrenal gland, mammary gland, placenta and kidney showed low expression whereas a series of other tissues, including skeletal muscle and different regions of brain show no expression. Similarity: Contains 1 C1q domain. Contains 1 collagen-like domain. Contains 1 EMI domain. Gene ID: 11117 Database links: Entrez Gene: 11117 Human Omim: 130660 Human SwissProt: Q9Y6C2 Human Unigene: 63348 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
弹性蛋白微原纤维界面因子1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 信号转导 转录调节因子 糖蛋白 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid