贰贬顿2蛋白抗体
规格：1尘驳/1尘濒
英文名： EHD2
别名： EH domain containing 2; EH domain containing 3; EH domain containing protein 2; EH domain-containing protein 2; EHD 2; Ehd2; EHD2_HUMAN; EHD3; FLJ96617; PAST 2; PAST homolog 2; PAST2.
分子量： 60kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EHD2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞膜
贰贬顿2蛋白抗体产物介绍：background: This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene produc贰贬顿2蛋白抗体 participates in the endocytic pathway. [provided by RefSeq, Jul 2008] Function: Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP. Subcellular Location: Cell membrane. Endosome membrane. Colocalizes with GLUT4 in intracellular tubulovesicular structures that are 贰贬顿2蛋白抗体associated with cortical F-actin. Tissue Specificity: Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle. Similarity: Contains 1 EF-hand domain. Contains 1 EH domain. Gene ID: 30846 Database links: Entrez Gene: 30846 Human Entrez Gene: 538348 Cow Entrez Gene: 259300 Mouse Entrez Gene: 361512 Rat Omim: 605890 Human SwissProt: Q9NZN4 Human SwissProt: Q8BH64 Mouse SwissProt: Q4V8H8 Rat Unigene: 631554 Human Unigene: 138215 Mouse Unigene: 438817 Mouse Unigene: 16016 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
贰贬顿2蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid