骋蛋白偶联受体183抗体
规格：1尘驳/1尘濒
英文名： GPR183
别名： ebi 2; EBI2; EBV induced G protein coupled receptor 2; EBV-induced G-protein coupled receptor 2; ebv-induced gene 2; Epstein-Barr virus-induced gene 2; Epstein Barr virus induced gene 2; epstein-barr
分子量： 41kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EBV Indu
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞膜
骋蛋白偶联受体183抗体产物介绍：background: Epstein-Barr virus-induced gene 2 is a 357 amino acid multi pass membrane protein. It is expressed in B-lymphocytes and lymphoid tissues and may function in the modulation of the immune system. Out of the nine genes that are induced by the Epstein-Barr virus, Ebi2 exhibits the highest levels of up-regulation. Ebi2 is a G-protein coupled receptor that signals through the G-protein G錳. Ebi2 contains seven hydrophobic transmembrane regions and a putative N-linked glycosylation site at its extracellular N-terminus骋蛋白偶联受体183抗体. Ebi2 is believed to be involved in regulating the effects of the Epstein-Barr virus on B-lymphocytes. In addition, Ebi2 may play a role mediating normal lymphocyte functions. Function: Orphan receptor that plays a central role during humoral immunity. Promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity). Signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha. Subcellular Location:骋蛋白偶联受体183抗体 Cell membrane. Tissue Specificity: Expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. Also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the urogenital system and brain. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 1880 Database links: Entrez Gene: 1880 Human Entrez Gene: 769212 Chicken Entrez Gene: 540287 Cow Entrez Gene: 100050745 Horse Entrez Gene: 100388743 Marmoset (common) Entrez Gene: 321019 Mouse Entrez Gene: 679975 Rat Omim: 605741 Human SwissProt: Q1RMI1 Cow SwissProt: P32249 Human SwissProt: Q3U6B2 Mouse SwissProt: D4A7K7 Rat Unigene: 784 Human Unigene: 265618 Mouse Unigene: 179130 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骋蛋白偶联受体183抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 **及病毒 G蛋白偶联受体 G蛋白信号 细胞膜蛋白
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid