热休克蛋白75抗体
规格:1尘驳/1尘濒
英文名: TRAP1/HSP75
别名: TRAP1; TRAP-1; Heat shock protein 75; Heat shock protein 75 kDa mitochondrial; HSP 75; HSP 90L; HSP75; HSP90L; TNF receptor associated protein 1; TNFR associated protein 1; TRAP 1; Tumor necrosis fact
分子量: 74kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HSP75
交叉反应:Human, Mouse, Rat, Chicken, Horse, Rabbit,
细胞定位:
热休克蛋白75抗体产物介绍:background: This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] Function:热休克蛋白75抗体Chaperone that expresses an ATPase activity. Subunit: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. Binds to RB1. Subcellular Location: Mitochondrion. Tissue Specificity: Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta. Similarity: Belongs to the heat shock protein 90 family. Gene ID: 10131 Database links: Entrez Gene: 10131 Human Entrez Gene: 68015 Mouse Entrez Gene: 287069 Rat Entrez Gene: 416666 Chicken Entrez Gene: 514472 Cow Omim: 606219 Human SwissProt: Q2TBI4 Cow SwissProt: Q12931 热休克蛋白75抗体Human SwissProt: Q9CQN1 Mouse SwissProt: Q5XHZ0 Rat Unigene: 30345 Human Unigene: 123366 Mouse Unigene: 144695 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 信号传导(Signaling Intermediates) HSP75/TRAP-1与TNF受体发生相互作用,可产生促进TNF的信号转导。
热休克蛋白75抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 信号转导 细胞凋亡 转录调节因子 线粒体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid