双特异性磷酸酶抗体18抗体
规格：1尘驳/1尘濒
英文名： DUSP18
别名： Dual specificity protein phosphatase 18; DUS18_HUMAN; DUSP18; LMW-DSP20; LMWDSP20; Low molecular weight dual specificity phosphatase 20.
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DUSP18
交叉反应：Human, Mouse, Rat, Horse,
细胞定位：细胞核 细胞浆
双特异性磷酸酶抗体18抗体产物介绍：background: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009] Function: Can dephosphor双特异性磷酸酶抗体18抗体ylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). Subcellular Location:双特异性磷酸酶抗体18抗体 Cytoplasm. Nucleus. Tissue Specificity: Widely expressed with highest levels in liver, brain, ovary and testis. Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Contains 1 tyrosine-protein phosphatase domain. Gene ID: 150290 Database links: Entrez Gene: 150290 Human Entrez Gene: 75219 Mouse Omim: 611446 Human SwissProt: Q8NEJ0 Human SwissProt: Q8VE01 Mouse Unigene: 517544 Human Unigene: 32588 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
双特异性磷酸酶抗体18抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid