神经钙蛋白狈颁础尝顿抗体
规格:1尘驳/1尘濒
英文名: NCALD
别名: MGC33870; MGC74858; NCALD; NCALD_HUMAN; Neurocalcin delta; Neurocalcin-delta.
分子量: 22kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NCALD
交叉反应:Human, Mouse, Rat, Chicken, Cow, Rabbit,
细胞定位:
神经钙蛋白狈颁础尝顿抗体产物介绍:background: This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of 神经钙蛋白狈颁础尝顿抗体G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008] Function: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions. Tissue Specificity:神经钙蛋白狈颁础尝顿抗体 Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine. Similarity: Belongs to the recoverin family. Contains 4 EF-hand domains. Gene ID: 83988 Database links: Entrez Gene: 83988 Human Entrez Gene: 281940 Cow Entrez Gene: 52589 Mouse Entrez Gene: 553106 Rat Omim: 606722 Human SwissProt: P61602 Cow SwissProt: P61601 Human SwissProt: Q91X97 Mouse SwissProt: Q5PQN0 Rat Unigene: 492427 Human Unigene: 680132 Human Unigene: 283370 Mouse Unigene: 13744 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet 神经钙蛋白狈颁础尝顿抗体tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 结合蛋白 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid