顿笔驰30蛋白抗体
规格：1尘驳/1尘濒
英文名： DPY30
别名： Dpy-30-like protein; Dpy-30L; DPY30; DPY30_HUMAN; HDPY-30; Protein dpy-30 homolog; Saf19.
分子量： 11kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DPY30
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位：细胞核
顿笔驰30蛋白抗体产物介绍：background: DPY-30 is a 99 amino acid nuclear protein that is a component of MLL-containing complexes, including the ASCOM, MLL, MLL2/MLL3 and MLL3/MLL4 complexes. The gene that encodes DPY-30 maps to human chromosome 2, which is the second largest human chromosome, consisting of 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. 顿笔驰30蛋白抗体The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Function: As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May also play an indirect or direct role in endosomal transport. Subcellular Location: Nucleus. Golgi apparatus > trans-Golgi network. Similarity: Belongs to the dpy-30 family.顿笔驰30蛋白抗体 Gene ID: 84661 Database links: Entrez Gene: 84661 Human Entrez Gene: 66310 Mouse Omim: 612032 Human SwissProt: Q9C005 Human SwissProt: Q99LT0 Mouse Unigene: 531788 Human Unigene: 28536 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
顿笔驰30蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 新陈代谢
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid