原发性纤毛运动障碍相关蛋白顿笔颁顿抗体
规格:1尘驳/1尘濒
英文名: DPCD
别名: Deleted in a mouse model of primary ciliary dyskinesia; DKFZp566F084; dpcd; DPCD protein; DPCD_HUMAN; OTTHUMP00000020329; Protein DPCD; RP11 529I10.4; RP11-529I10.4.
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DPCD
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
细胞定位:
原发性纤毛运动障碍相关蛋白顿笔颁顿抗体产物介绍:background: DPCD is a 203 amino acid protein that is expressed at higher levels during ciliated cell differentiation, suggesting that DPCD plays a role in the function or formation of ciliated cells. In primary ciliary dyskinesia (PCD), an autosomal recessive disease that is caused by mutations affecting the proper function of cilia, an exon in the DPCD gene is deleted. The phenotype of PCD is variable, though it may include symptoms such as sinus inverse totalis, infertility or otitis media. In severe cases,原发性纤毛运动障碍相关蛋白顿笔颁顿抗体 patients develop end-stage bronchiectasis and require a lung transplantation. DPCD is highly expressed in testis, with weak expression in heart, pancreas and skeletal muscle. Function: May play a role in the formation or function of ciliated cells. Tissue Specificity: Highly expressed in the testis. Weakly expressed in pancreas, skeletal muscle and heart. Expression increases during ciliated cell原发性纤毛运动障碍相关蛋白顿笔颁顿抗体 differentiation. Similarity: Belongs to the DPCD family. Gene ID: 25911 Database links: Entrez Gene: 25911 Human Entrez Gene: 516908 Cow Entrez Gene: 477800 Dog Entrez Gene: 226162 Mouse Entrez Gene: 294004 Rat SwissProt: Q24K21 Cow SwissProt: Q9BVM2 Human SwissProt: Q8BPA8 Mouse SwissProt: Q6AYM4 Rat Unigene: 658128 Human Unigene: 21978 Mouse Unigene: 50057 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原发性纤毛运动障碍相关蛋白顿笔颁顿抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 细胞分化
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid