顿狈础闯叠11蛋白抗体
规格：1尘驳/1尘濒
英文名： DNAJB11
别名： ABBP-2; ABBP2; APOBEC1 binding protein 2; APOBEC1-binding protein 2; DJ9; DJB11_HUMAN; DnaJ (Hsp40) homolog subfamily B member 11; DnaJ homolog subfamily B member 11; DnaJ protein homolog 9; DNAJB11;
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DNAJB11
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位：
顿狈础闯叠11蛋白抗体产物介绍：background: DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a C-terminal cysteine-rich region (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008] Function: Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins 顿狈础闯叠11蛋白抗体that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. Subcellular Location: Endoplasmic reticulum lumen. Associated with the ER membrane in a C-terminally epitope-tagged construct. Tissue Specificity: Widely 顿狈础闯叠11蛋白抗体expressed. Post-translational modifications: Contains high-mannose Endo H-sensitive carbohydrates. Cys-169, Cys-171, Cys-193 and Cys-196 form intramolecular disulfide bonds. The preferential partner for each Cys is not known. Similarity: Contains 1 J domain. Gene ID: 51726 Database links: Entrez Gene: 51726 Human Entrez Gene: 67838 Mouse Entrez Gene: 360734 Rat Omim: 611341 Human SwissProt: Q9UBS4 Human SwissProt: Q99KV1 Mouse SwissProt: Q6TUG0 Rat Unigene: 317192 Human Unigene: 37516 Mouse Unigene: 477367 Mouse Unigene: 14603 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
顿狈础闯叠11蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid