胰岛素样生长因子结合蛋白3抗体
规格:1尘驳/1尘濒
英文名: IGFBP3
别名: IGF BP3; IGF-BP3; Acid stable subunit of the 140 K IGF complex; Binding protein 29; Binding protein 53; BP 53; BP53; Growth hormone dependent binding protein; IBP 3; IBP3; IGF binding protein 3; IGFBP
分子量: 30-35kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human IGFBP3
交叉反应:Human, Mouse, Rat,
细胞定位:分泌型蛋白
胰岛素样生长因子结合蛋白3抗体产物介绍:background: GFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms,胰岛素样生长因子结合蛋白3抗体 have been characterized. Subcellular Location: Secreted. Tissue Specificity: Expressed by most tissues. Present in plasma. Post-translational modifications: Phosphorylation sites are present in the extracelllular medium. Similarity: Contains 1 IGFBP N-terminal domain. Contains 1 thyroglobulin type-1 domain. Gene ID: 3486 Database links: Entrez Gene: 3486 Human Entrez Gene: 16009 Mouse胰岛素样生长因子结合蛋白3抗体 Entrez Gene: 24484 Rat Omim: 146732 Human SwissProt: P17936 Human SwissProt: P47878 Mouse SwissProt: P15473 Rat Unigene: 450230 Human Unigene: 697535 Human Unigene: 29254 Mouse Unigene: 26369 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胰岛素样生长因子结合蛋白3抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 生长因子和** 转录调节因子 糖尿病
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid