二甲基甘氨酸脱氢酶抗体
规格：1尘驳/1尘濒
英文名： DMGDH
别名： Dimethylglycine dehydrogenase; Dimethylglycine dehydrogenase, mitochondrial; Dmgdh; M2GD_HUMAN; ME2GLYDH; mitochondrial.
分子量： 91kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DMGDH
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：
二甲基甘氨酸脱氢酶抗体产物介绍：background: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Subcellular Location: Mitochondrion. DISEASE: Defects in DMGDH are the cause of DMGDH deficiency 二甲基甘氨酸脱氢酶抗体(DMGDHD) [MIM:605850]. DMGDHD is a disorder characterized by fish odor, muscle fatigue with increased serum creatine kinase. Biochemically it is characterized by an increase of N,N-dimethylglycine (DMG) in serum and urine. Similarity: Belongs to the GcvT family. Gene ID: 29958 Database links: Entrez Gene: 29958 Human Entrez Gene: 504453 Cow Entrez Gene: 488935 Dog Entrez Gene: 100724353 Guinea pig 二甲基甘氨酸脱氢酶抗体Entrez Gene: 100073267 Horse Entrez Gene: 74129 Mouse Entrez Gene: 100525563 Pig Entrez Gene: 100340207 Rabbit Entrez Gene: 245961 Rat Omim: 605849 Human SwissProt: Q9UI17 Human SwissProt: Q9DBT9 Mouse SwissProt: Q63342 Rat Unigene: 655653 Human Unigene: 21789 Mouse Unigene: 3646 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
二甲基甘氨酸脱氢酶抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 新陈代谢 线粒体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid