卷曲螺旋蛋白顿滨齿1抗体
规格：1尘驳/1尘濒
英文名： DIXDC1
别名： CCD1; Ccd1Aalpha1L; Ccd1Abeta1L; Ccd1BalphaL; Ccd1BbetaL; Ccd1CL; Coiled coil DIX1; Coiled coil protein DIX1; Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain containing 1; DIX domain containing
分子量： 77kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DIXDC1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞浆
卷曲螺旋蛋白顿滨齿1抗体产物介绍：background: The protein encoded by this gene is a positive regulator of the Wnt signaling pathway. The encoded protein is found associated with gamma tubulin at the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013] Function: Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2. Subcellular Location: Cytoplasm; Cell junction; focal adhesion. Associated with actin stress卷曲螺旋蛋白顿滨齿1抗体 fiber at the filament ends and Cytoplasm; cytosol. Colocalizes with gamma-tubulin at the centrosome, both during interphase and mitosis. Tissue Specificity: Ubiquitously expressed with higher expression in cardiac and skeletal muscles. Post-translational modifications: Phosphorylated on tyrosine and serine residues. Polyubiquitinated, leading to its proteasomal degradation. WNT3A signaling increases 卷曲螺旋蛋白顿滨齿1抗体DIXDC1 protein levels by inhibiting its ubiquitination and subsequent degradation. Similarity: Belongs to the DIXDC1 family. Contains 1 CH (calponin-homology) domain. Contains 1 DIX domain. Gene ID: 85458 Database links: Entrez Gene: 85458 Human Omim: 610493 Human SwissProt: Q155Q3 Human Unigene: 655626 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
卷曲螺旋蛋白顿滨齿1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 信号转导 干细胞 激酶和磷酸酶 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid