脱支酶同源蛋白顿叠搁1抗体
规格:1尘驳/1尘濒
英文名: DBR1
别名: DBR1; DBR1_HUMAN; Debranching enzyme homolog 1 (S. cerevisiae); Lariat debranching enzyme; RNA lariat debranching enzyme.
分子量: 62kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DBR1
交叉反应:Human, Mouse, Rat, Dog, Cow, Sheep,
细胞定位:细胞核
脱支酶同源蛋白顿叠搁1抗体产物介绍:background: The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2'-5' prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication. [provided by RefSeq, Nov 2011] Function: Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into脱支酶同源蛋白顿叠搁1抗体 linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via a RNA lariat intermediate in cDNA synthesis. Subcellular Location: Nucleus. Similarity: Belongs to脱支酶同源蛋白顿叠搁1抗体 the lariat debranching enzyme family. Gene ID: 51163 Database links: Entrez Gene: 51163 Human Entrez Gene: 83703 Mouse Entrez Gene: 681234 Rat Omim: 607024 Human SwissProt: Q9UK59 Human SwissProt: Q923B1 Mouse Unigene: 477700 Human Unigene: 31324 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脱支酶同源蛋白顿叠搁1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid