甘油二酯激酶γ/顿骋碍-γ抗体
规格:1尘驳/1尘濒
英文名: DGKG
别名: DAG kinase gamma; DAGK3; DGK gamma; DGKG; DGKG_HUMAN; diacylglycerol kinase gamma 90kDa; Diacylglycerol kinase gamma; Diglyceride kinase; Diglyceride kinase gamma.
分子量: 89kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DGKE
交叉反应:Human, Mouse, Rat, Dog, Horse, Rabbit,
细胞定位:细胞膜
甘油二酯激酶γ/顿骋碍-γ抗体产物介绍:background: This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found 甘油二酯激酶γ/顿骋碍-γ抗体for this gene. [provided by RefSeq, Jul 2008] Function: DGKG (Diacylglycerol kinase gamma ) reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid. This enzyme initiates resynthesis of phosphoinositides consumed by phospholipase C during cellular signal transduction. DGK gamma is one of multiple DGK isozymes found in animal cells. It is expressed abundantly in the human retina and to a much lesser extent in the brain. Other tissues contain extremely low levels. Subcellular Location: 甘油二酯激酶γ/顿骋碍-γ抗体Cell Membrane and Cytoplasmic. Gene ID: 1608 Database links: Entrez Gene: 1608 Human Entrez Gene: 110197 Mouse Entrez Gene: 25666 Rat Omim: 601854 Human SwissProt: P49619 Human SwissProt: Q2M1H4 Human SwissProt: Q5FWG1 Human SwissProt: Q91WG7 Mouse SwissProt: P49620 Rat Unigene: 683449 Human Unigene: 194986 Mouse Unigene: 10544 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甘油二酯激酶γ/顿骋碍-γ抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid