狄乔治(顿颈骋别辞谤驳别)氏综合征相关蛋白抗体
规格：1尘驳/1尘濒
英文名： DGCR14
别名： DGCR14; DGS H; DGS I; DGSH; DGSI; DiGeorge syndrome critical region gene 14; DiGeorge syndrome critical region gene DGSI; DiGeorge syndrome critical region protein 14; DiGeorge syndrome gene H; DiGeor
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DGCR14
交叉反应：Human, Mouse, Rat, Dog, Rabbit,
细胞定位：细胞核
狄乔治(顿颈骋别辞谤驳别)氏综合征相关蛋白抗体产物介绍：background: DGCR14 is a 476 amino acid nuclear protein that belongs to the DGCR14 family. DGCR14 is believed to play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (DiGeorge syndrome chromosome region, or DGCR). 狄乔治(顿颈骋别辞谤驳别)氏综合征相关蛋白抗体This protein localizes to the nucleus and co-purifies with C complex spliceosomes. Function: DiGeorge syndrome critical region 14, DGCR14 has been identified in the spliceosome C complex and may be involved in pre-mRNA splicing. May have a role in velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies,狄乔治(顿颈骋别辞谤驳别)氏综合征相关蛋白抗体 conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and facial anomalies. Most cases of this syndrome involve a deletion of chromosome 22q11.2 in the DiGeorge syndrome chromosome region. Subcellular Location: Nuclear Similarity: Belongs to the DGCR14 family. Gene ID: 8220 Database links: Entrez Gene: 8220 Human Omim: 601755 Human SwissProt: Q96DF8 Human Unigene: 517407 Human Unigene: 686112 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
狄乔治(顿颈骋别辞谤驳别)氏综合征相关蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 发育生物学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid