二酰基甘油酰基转移酶2样蛋白4抗体
规格：1尘驳/1尘濒
英文名： DGAT2L4
别名： Acyl CoA wax alcohol acyltransferase 2; acyl-CoA retinol O-fatty-acyltransferase; ARAT; AWAT2; DC4; Diacylglycerol O acyltransferase 2 like 4; Diacylglycerol O acyltransferase candidate 4; diacylglyce
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DGAT2L4
交叉反应：Human, Mouse, Rat,
细胞定位：
二酰基甘油酰基转移酶2样蛋白4抗体产物介绍：background: This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters. [provided by RefSeq, May 2010] Function: Acyltransferase二酰基甘油酰基转移酶2样蛋白4抗体 that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have 2 acylglycerol O acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters; however this activity is unclear in vivo. Subcellular Location: Endoplasmic reticulum membrane; 二酰基甘油酰基转移酶2样蛋白4抗体Multipass membrane protein. Tissue Specificity: Abundant in tissues rich in sebaceous glands such as the preputial gland and eyelid. Highly expressed in skin, where it is primarily restricted to undifferentiated peripheral sebocytes. Also expressed at lower level in other tissues except pancreas. Similarity: Belongs to the diacylglycerol acyltransferase family. Gene ID: 158835 Database links: Entrez Gene: 158835 Human Entrez Gene: 245532 Mouse Entrez Gene: 302425 Rat SwissProt: Q6E213 Human SwissProt: Q6E1M8 Mouse Unigene: 661507 Human Unigene: 118171 Mouse Unigene: 220750 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
二酰基甘油酰基转移酶2样蛋白4抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid