内质网退化蛋白2抗体
规格：1尘驳/1尘濒
英文名： DERL2
别名： Carcinoma related; Carcinoma related; derlin 2; CGI 101; DERL2_HUMAN; Degradation in endoplasmic reticulum protein 2; DER 2; Der1 like domain family member 2; Der1-like protein 2; DER2; DERL 2; Derlin
分子量： 27kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DERL2
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit,
细胞定位：
内质网退化蛋白2抗体产物介绍：background: Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM, Mar 2008] Function: DERL2 (Derlin 2) may be involved in the degradation process内质网退化蛋白2抗体 of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation. Subcellular Location: Endoplasmic reticulum; Multi-pass membrane protein. Similarity: Belongs to the derlin family. Gene ID: 51009 Database内质网退化蛋白2抗体 links: Entrez Gene: 51009 Human Entrez Gene: 116891 Mouse Omim: 610304 Human SwissProt: Q9GZP9 Human SwissProt: Q8BNI4 Mouse Unigene: 286131 Human Unigene: 28131 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
内质网退化蛋白2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 转运蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid