白介素-1受体相关激酶2抗体
规格：1尘驳/1尘濒
英文名： IRAK2
别名： Interleukin 1 receptor associated kinase like 2; il1rak2; Interleukin 1 receptor associated kinase 2; Interleukin-1 receptor-associated kinase-like 2; IRAK 2; IRAK-2; Irak2; IRAK2_HUMAN; MGC150550.
分子量： 69kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IRAK2
交叉反应：Human, Mouse, Rat,
细胞定位：
白介素-1受体相关激酶2抗体产物介绍：background: IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B. Function: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Subunit: Interacts with MYD88. IL-1 stimulation白介素-1受体相关激酶2抗体 leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1. Tissue Specificity: Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes. Similarity:白介素-1受体相关激酶2抗体 Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily. Contains 1 death domain. Contains 1 protein kinase domain. Gene ID: 3656 Database links: Entrez Gene: 3656 Human Entrez Gene: 108960 Mouse Entrez Gene: 362418 Rat Omim: 603304 Human SwissProt: O43187 Human SwissProt: Q8CFA1 Mouse SwissProt: Q5R810 Orangutan SwissProt: Q4QQS0 Rat Unigene: 449207 Human Unigene: 152142 Mouse Unigene: 17123 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 激酶和磷酸酶（Kinases and Phosphatases）
白介素-1受体相关激酶2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid