多药耐药相关蛋白4抗体
规格:1尘驳/1尘濒
英文名: MRP4/ABCC4
别名: ABCC 4; ABCC4; ATP binding cassette sub family C (CFTR/MRP) member 4; ATP binding cassette sub family C member 4; bA464I2.1 (ATP binding cassette, sub-family C (CFTR/MRP) member 4); bA464I2.1; Canalic
分子量: 149kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MRP4
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Guinea Pig,
细胞定位:细胞膜
多药耐药相关蛋白4抗体产物介绍:background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular多药耐药相关蛋白4抗体 detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008]. Function: May be an organic anion pump relevant to cellular detoxification. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed, with particularly high levels in prostate, but is barely detectable in 多药耐药相关蛋白4抗体liver. Similarity: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. Contains 2 ABC transmembrane type-1 domains. Contains 2 ABC transporter domains. Gene ID: 10257 Database links: Entrez Gene: 10257 Human Entrez Gene: 239273 Mouse Omim: 605250 Human SwissProt: O15439 Human Unigene: 508423 Human Unigene: 40537 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多药耐药相关蛋白4抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid