癌基因删去蛋白顿滨颁贰1抗体
规格：1尘驳/1尘濒
英文名： DDX26/DICE1
别名： DBI 1; DBI-1; DBI1; DDX26; DDX26A; DEAD box protein; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26; Deleted in cancer 1; DICE1; DKFZp434B105; HDB; Int6; INT6_HUMAN; Integrator complex subunit 6; INT
分子量： 100kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DDX26/DI
交叉反应：Human, Mouse, Rat, Pig, Horse, Rabbit,
细胞定位：细胞核
癌基因删去蛋白顿滨颁贰1抗体产物介绍：background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.癌基因删去蛋白顿滨颁贰1抗体 [provided by RefSeq, Jul 2008] Function: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an 癌基因删去蛋白顿滨颁贰1抗体ectopic expression suppressing tumor cell growth. Subcellular Location: Nucleus. Tissue Specificity: Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Similarity: Belongs to the Integrator subunit 6 family. Contains 1 VWFA domain. Gene ID: 26512 Database links: Entrez Gene: 26512 Human Omim: 604331 Human SwissProt: Q9UL03 Human Unigene: 439440 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
癌基因删去蛋白顿滨颁贰1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 转运蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid