二酰基甘油脂肪酶β/DAGLβ 抗体
规格:1尘驳/1尘濒
英文名: DAGLB
别名: Daglb; DGL beta; DGL-beta; DGLB_HUMAN; Diacylglycerol lipase beta; KCCR13L; Sn1 specific diacylglycerol lipase beta; Sn1-specific diacylglycerol lipase beta.
分子量: 74kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DAGLB
交叉反应:Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞膜
二酰基甘油脂肪酶β/DAGLβ 抗体产物介绍:background: KCCR13L, is a 672 amino acid multi-pass membrane protein that belongs to the AB hydrolase superfamily. DAGL beta uses calcium as a cofactor to catalyze the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), a reaction that is required for axonal growth and for retrograde synaptic signaling at mature synapses. DAGL beta functions二酰基甘油脂肪酶β/DAGLβ 抗体 at an optimal pH of 7 and its activity is inhibited by p-hydroxy-mercuri-benzoate and HgCl2, but not PMSF. There are three isoforms of DAGL beta that are produced as a result of alternative splicing events. Function: Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses. Subcellular Location: Cell membrane. Similarity: Belongs to the AB hydrolase superfamily. Lipase family二酰基甘油脂肪酶β/DAGLβ 抗体. Gene ID: 221955 Database links: Entrez Gene: 221955 Human Entrez Gene: 231871 Mouse SwissProt: Q8NCG7 Human SwissProt: Q91WC9 Mouse Unigene: 487498 Human Unigene: 469963 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
二酰基甘油脂肪酶β/DAGLβ 抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid