脑神经细胞胞浆蛋白1抗体
规格:1尘驳/1尘濒
英文名: NSG1/D4S234E
别名: D4S234E; Brain neuron cytoplasmic protein 1; Brain specific mRNA b; Bsmrb; Neuron-specific gene family member 1; Neuron-specific protein family member 1; NSG1; NSG1_HUMAN; PEP1; P21; D4S234; NEEP21.
分子量: 21kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NSG1
交叉反应:Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep,
细胞定位:
脑神经细胞胞浆蛋白1抗体产物介绍:background: NSG1 is a single pass type II membrane protein belonging to the NSG family. It is highly expressed during neuronal maturation but its expression is downregulated in tissues. NEEP21 predominantly localizes to Rab 4-positive early endosomes in the somatodendritic neuronal compartment and is essential for proper receptor sorting and recycling in neurons.脑神经细胞胞浆蛋白1抗体 It associates with GRIP1 and GluR-2 and mediates the surface expression of GluR-2. When this interaction is interrupted, GluR-2 accumulates in early endosomes and leads to changes in evoked synaptic current properties. In addition, NEEP21 forms a complex with the SNARE protein, Syntaxin 13 (also known as Syntaxin 12), and participates in the recycling of transferrin receptors (TFRs) and NTR2 (neurotensin receptor 2). 脑神经细胞胞浆蛋白1抗体Subcellular Location: Golgi apparatus membrane. Similarity: Belongs to the NSG family. Gene ID: 27065 Database links: Entrez Gene: 27065 Human Entrez Gene: 18196 Mouse Entrez Gene: 25247 Rat Omim: 607645 Human SwissProt: P42857 Human SwissProt: Q62092 Mouse SwissProt: P02683 Rat Unigene: 518595 Human Unigene: 7414 Mouse Unigene: 2865 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑神经细胞胞浆蛋白1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid