补体颁1辩肿瘤坏死因子相关蛋白4抗体
规格：1尘驳/1尘濒
英文名： CTRP4
别名： C1q and tumor necrosis factor related protein 4; C1QTNF4; C1QT4_HUMAN; Complement C1q tumor necrosis factor related protein; ZACRP4.
分子量： 35kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CTRP4
交叉反应：Human, Mouse, Rat, Dog, Pig,
细胞定位：细胞浆
补体颁1辩肿瘤坏死因子相关蛋白4抗体产物介绍：background: C1QTNF4 is a 329 amino acid secreted protein that contains two C1q domains and may play a role in immune homeostasis and various other events throughout the cell. The gene encoding CTRP4 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Function: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism补体颁1辩肿瘤坏死因子相关蛋白4抗体 and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure 补体颁1辩肿瘤坏死因子相关蛋白4抗体of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of mouse CTRP4 have been reported. Subcellular Location: Secreted Similarity: Contains 2 C1q domains. Gene ID: 114900 Database links: Entrez Gene: 114900 Human Entrez Gene: 67445 Mouse GenBank: AAH35628 Human SwissProt: Q9BXJ3 Human SwissProt: Q4ZJN5 Mouse SwissProt: Q8R066 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
补体颁1辩肿瘤坏死因子相关蛋白4抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid