羧基端小结构域磷酸酶2抗体
规格：1尘驳/1尘濒
英文名： CTDSP2
别名： Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 2; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; CTDS2_HUMAN; Ctdsp2; NIF2; NLI interacting fac
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CTDSP2
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
羧基端小结构域磷酸酶2抗体产物介绍：Function: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. Subunit羧基端小结构域磷酸酶2抗体: Monomer (By similarity). Interacts with REST. Subcellular Location: Nucleus (By similarity). Tissue Specificity: Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver. Similarity: Contains 1 FCP1 homology domain. Gene ID: 10106 Database links: Entrez Gene: 10106 Human Entrez Gene: 506115 Cow Entrez Gene: 52468 Mouse Omim: 608711 Human SwissProt:羧基端小结构域磷酸酶2抗体 O14595 Human SwissProt: Q8BX07 Mouse Unigene: 524530 Human Unigene: 29490 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
羧基端小结构域磷酸酶2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 染色质和核信号 信号转导 肿瘤细胞生物标志物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid