富含半胱氨酸与表皮生长因子样蛋白1抗体
规格：1尘驳/1尘濒
英文名： CRELD1
别名： Atrioventricular septal defect 2; AVSD2; CIRRIN; CREL1_HUMAN; CRELD1; Cysteine rich with EGF like domains 1; Cysteine-rich with EGF-like domain protein 1; DKFZP566D213.
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CRELD1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞膜
富含半胱氨酸与表皮生长因子样蛋白1抗体产物介绍：background: This gene encodes a member of a subfamily of epidermal growth factor-related proteins. The encoded protein is characterized by a cysteine-rich with epidermal growth factor-like domain. This protein may function as a cell adhesion molecule. Mutations in this gene are the cause of atrioventricular septal defect. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010] Function: Highly expressed in fetal lung, liver, kidney, heart, brain and skeletal muscle.富含半胱氨酸与表皮生长因子样蛋白1抗体 Weakly expressed in placenta, fetal brain, and lung, liver, kidney and pancreas. Subcellular Location: Membrane. DISEASE: Defects in CRELD1 may be the cause of susceptibility to atrioventricular septal defect type 2 (AVSD2) [MIM:606217]. AVSD is a spectrum of cardiac malformations that result in a persistent common atrioventricular canal. The complete form of AVSD involves underdevelopment of the lower part of the atrial septum and the upper part of the ventricular septum. A less severe form, known as partial AVSD or ostium primum 富含半胱氨酸与表皮生长因子样蛋白1抗体atrial septal defect has a deficiency of the atrial septum. Complete AVSD are clinically apparent at birth, whereas less severe forms, such as an isolated cleft mitral valve or small defects of the atrial or ventricular septa may go undetected. Similarity: Belongs to the CRELD family. Contains 2 EGF-like domains. Contains 2 FU (furin-like) repeats. Gene ID: 78987 Database links: Entrez Gene: 78987 Human Entrez Gene: 171508 Mouse Entrez Gene: 312638 Rat Omim: 607170 Human SwissProt: Q96HD1 Human SwissProt: Q91XD7 Mouse SwissProt: Q4V7F2 Rat Unigene: 9383 Human Unigene: 41593 Mouse Unigene: 6461 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
富含半胱氨酸与表皮生长因子样蛋白1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学 细胞粘附分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid