降钙素基因相关肽受体颁搁颁笔抗体
规格：1尘驳/1尘濒
英文名： CRCP
别名： Calcitonin gene related peptide receptor component; Calcitonin gene related peptide receptor component protein; Calcitonin gene-related peptide-receptor component protein; CGRP receptor component prot
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CRCP
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位：细胞核 细胞膜
降钙素基因相关肽受体颁搁颁笔抗体产物介绍：background: This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes 降钙素基因相关肽受体颁搁颁笔抗体small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway.降钙素基因相关肽受体颁搁颁笔抗体 Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues. Subcellular Location: Nucleus. Cell membrane. Tissue Specificity: Ubiquitous. Most prevalent in testis. Similarity: Belongs to the eukaryotic RPC9 RNA polymerase subunit family. Gene ID: 27297 Database links: Entrez Gene: 27297 Human Omim: 606121 Human SwissProt: O75575 Human Unigene: 300684 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
降钙素基因相关肽受体颁搁颁笔抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid