等上游刺激因子1抗体
规格:1尘驳/1尘濒
英文名: USF-1
别名: bHLHb11; USF1; USF 1; Class B basic helix-loop-helix protein 11; FCHL 1; FCHL; FCHL1; HGNC:12593; HYPLIP 1; HYPLIP1; Major late transcription factor 1; Major late transcription factor; MLTF; MLTF I; M
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human USF-1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:
等上游刺激因子1抗体产物介绍:background: This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene. Alternate Names: upstream stimulatory factor 1; transcription factor USF-1; bHLHb11; Upstream stimulatory factor 1; Major late transcription factor 1. Function: Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a homodimer or a 等上游刺激因子1抗体heterodimer (USF1/USF2). Interacts with varicella-zoster virus IE62 protein. Subcellular Location: Nucleus. DISEASE: Hyperlipidemia combined 1 (HYPLIP1) [MIM:602491]: A disorder characterized by a variable pattern of elevated levels of serum total cholesterol, triglycerides or both. It is observed in a percentage of individuals with premature coronary heart disease. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. Similarity: Contains 1 bHLH (basic helix-loop-helix) domain. Gene ID: 7391 Database links: Entrez Gene: 等上游刺激因子1抗体7391 Human Entrez Gene: 22278 Mouse Entrez Gene: 83586 Rat Omim: 191523 Human SwissProt: P22415 Human SwissProt: Q61069 Mouse Unigene: 414880 Human Unigene: 8 Mouse Unigene: 10845 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 转录调节因子(Transcriptin Regulators) USF-1是调节血浆脂质代谢的重要基因,包括某些载脂蛋白和肝脂酶。
等上游刺激因子1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid