钙依赖膜结合蛋白颁辞辫颈苍别蛋白3抗体
规格:1尘驳/1尘濒
英文名: CPNE3
别名: Copine 3; Copine III; Copine-3; Copine3; CopineIII; CPN3; CPNE 3; CPNE3; CPNE3_HUMAN; KIAA0636; PRO1071.
分子量: 60kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CPNE3
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞膜
钙依赖膜结合蛋白颁辞辫颈苍别蛋白3抗体产物介绍:background: Copine 3 is a member of the copine family of evolutionarily conserved, soluble, calcium-dependent, membrane-binding proteins. Members of the copine family are involved in signal transduction and membrane trafficking. Copine 3 is ubiquitously expressed and contains two N-terminal C2 domains and one C-terminal VWFA (von Willebrand factor A) domain, which is also referred to as the A domain or the core domain. As is characteristic of the copine family, copine 3 functions in membrane trafficking and is capable of binding phospholipids in a calcium-dependent manner. Differing from other members of the copine family, copine 钙依赖膜结合蛋白颁辞辫颈苍别蛋白3抗体3 may possess some intrinsic kinase activity. Copine 3 exists as a monomer in the cytosol and undergoes a conformational change upon binding to calcium. Function: May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties. Tissue Specificity: Ubiquitous. Post-translational modifications: Phosphorylated on serine and threonine residues. Similarity: Belongs to the 钙依赖膜结合蛋白颁辞辫颈苍别蛋白3抗体copine family. Contains 2 C2 domains. Contains 1 VWFA domain. Gene ID: 8895 Database links: Entrez Gene: 8895 Human Entrez Gene: 615304 Cow Entrez Gene: 70568 Mouse Omim: 604207 Human SwissProt: O75131 Human SwissProt: Q8BT60 Mouse Unigene: 191219 Human Unigene: 38390 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙依赖膜结合蛋白颁辞辫颈苍别蛋白3抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 结合蛋白 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid