突触足蛋白抗体
规格：1尘驳/1尘濒
英文名： Synaptopodin
别名： 9030217H17RIK; 9130229N11; 9330140I15Rik; AW046661; SYNAPTOPODIN; KIAA1029; SYNPO; SYNPO_HUMAN.
分子量： 100kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Synaptop
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
突触足蛋白抗体产物介绍：background: Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. May be essential for the formation of spine apparatuses in spines of telencephalic neurons, involved in synaptic plasticity. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes. Subunit: Interacts with BAIAP1. Interacts with actin (By similarity). Interacts (via PPxY motifs) with WWC1 (via WW domains). Subcellular Location: Cytoplasm, cytoskeleton (By similarity). Cell junction, tight junction (By similarity). Perikaryon (By similarity). Cell projection, dendritic spine (By similarity).突触足蛋白抗体Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Cell junction, synapse (By similarity). Note=Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Asssociated with dendritic spines of a subset of synapses (By similarity). Tissue Specificity: Expressed in brain, namely in the olfactory bulb, cerebral cortex, striatum, and hippocampus, but not in the cerebellum. Also expressed in the podocytes of kidney glomeruli. In the hippocampus, mainly expressed in the principal cell layer of the dentate gyrus and突触足蛋白抗体 Ammon's horn. Similarity: Belongs to the synaptopodin family. Gene ID: 11346 Database links: Entrez Gene: 11346 Human Entrez Gene: 104027 Mouse Entrez Gene: 60324 Rat Omim: 608155 Human SwissProt: Q8N3V7 Human SwissProt: Q8CC35 Mouse SwissProt: Q9Z327 Rat Unigene: 435228 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. synaptopodin是一种与肌动蛋白微丝偶联的蛋白，其富含脯氨酸,为线状蛋白质，在动物体内表达于肾小球的足细胞和后脑的突触内，synaptopodin被认为是足细胞特异的分化成熟标志物。
突触足蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 信号转导 细胞凋亡 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid