铜转运蛋白2抗体
规格：1尘驳/1尘濒
英文名： COPT2
别名： AI604396; Copper transporter 2; COPT2; COPT2_HUMAN; CTR2; hCTR2; MGC117640; Probable low affinity copper uptake protein 2; RP23 64F17.2; SLC31A2; Solute carrier family 31 member 2; Solute carrier fami
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human COPT2
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞膜
铜转运蛋白2抗体产物介绍：background: The activity of a diverse subset of enzymes relies on the essential nutrient copper to perform important processes including signaling to the transcription and protein trafficking machinery, oxidative phosphorylation, iron mobilization, neuropeptide maturation, and normal development. Copper uptake requires tight regulation to ensure that sufficient copper is present in the cell to drive vital cellular processes, while avoiding the accumulation of copper to toxic levels. The copper transporter 2 (COPT2), also designated 铜转运蛋白2抗体CTR2 or Solute carrier family 31 member 2 (SLC31A2), is a 143 amino acid protein mediates the uptake of copper in mammalian cells. COPT2 has been shown to localize to the plasma membrane, endosomes and lysosomes, where it plays a role in maintaining copper homeostasis. COPT2 also mediates the uptake of the chemotherapeutic drugs cisplatin and carboplatin and may modulate the sensitivity and 铜转运蛋白2抗体toxicity of these drugs. Function: Involved in low-affinity copper uptake. Subcellular Location: Membrane. Tissue Specificity: Ubiquitous. Similarity: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily. Gene ID: 1318 Database links: Entrez Gene: 1318 Human Entrez Gene: 20530 Mouse Omim: 603088 Human SwissProt: O15432 Human SwissProt: Q9CPU9 Mouse Unigene: 24030 Human Unigene: 292539 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
铜转运蛋白2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转运蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid