颁补蝉辫补蝉别抑制剂颁翱笔蛋白抗体
规格：1尘驳/1尘濒
英文名： COP
别名： CAR16_HUMAN; CARD only domain-containing protein 1; CARD only protein; CARD16; Caspase recruitment domain family, member 16; Caspase recruitment domain-containing protein 16; Caspase-1 dominant-negati
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human COP1
交叉反应：Human, Chimpanzee, Gorilla
细胞定位：
颁补蝉辫补蝉别抑制剂颁翱笔蛋白抗体产物介绍：background: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response.颁补蝉辫补蝉别抑制剂颁翱笔蛋白抗体 Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2. Tissue Specificity: Widely expressed. Expressed at higher level in placenta, spleen, lymph node and bone marrow.颁补蝉辫补蝉别抑制剂颁翱笔蛋白抗体 Weakly or not expressed in thymus. Similarity: Contains 1 CARD domain. Gene ID: 114769 Database links: Entrez Gene: 114769 Human SwissProt: Q5EG05 Human Unigene: 348365 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
颁补蝉辫补蝉别抑制剂颁翱笔蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid