胶原蛋白9抗体
规格：1尘驳/1尘濒
英文名： Collagen IX
别名： Collagen alpha 1(IX) chain; Collagen type IX alpha 1; EDM6; MED; STL4.
分子量： 89kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Collagen
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
胶原蛋白9抗体产物介绍：background: Type IX collagen proteoglycan is a major component of hyaline cartilages where it is located on the surface of the collagen fibrils so that a collagenous domain of the molecule (called COL 3) and a non-collagenous domain (called NC4) project at periodic distances away from the surface of the fibrils. Function: Structural component of hyaline cartilage and vitreous of the eye. Subunit: Heterotrimer of an alpha 1(IX), an alpha 2(IX) and an alpha 3(IX) chain. Subcellular Location: Secreted, extracellular space, extracellular matrix (By similarity). Tissue Specificity: Cytoplasmic Post-translational modifications: Covalently linked to the telopeptides of type II collagen by胶原蛋白9抗体 lysine-derived cross-links. Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. DISEASE: Multiple epiphyseal dysplasia 6 (EDM6) [MIM:614135]: A generalized skeletal dysplasia associated with significant morbidity. Joint pain, joint deformity, waddling gait, and short stature are the main clinical signs and symptoms. Radiological examination of the skeleton shows delayed, irregular mineralization of the epiphyseal ossification centers and of the centers of the carpal and tarsal bones. Multiple epiphyseal dysplasia is broadly 胶原蛋白9抗体categorized into the more severe Fairbank and the milder Ribbing types. The Fairbank type is characterized by shortness of stature, short and stubby fingers, small epiphyses in several joints, including the knee, ankle, hand, and hip. The Ribbing type is confined predominantly to the hip joints and is characterized by hands that are normal and stature that is normal or near-normal. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the fibril-associated collagens with interrupted helices (FACIT) family. Contains 10 collagen-like domains. Contains 1 laminin G-like domain. Gene ID: 1297 Database links: Entrez Gene: 1297 Human Entrez Gene: 12839 Mouse Entrez Gene: 305104 Rat Omim: 120210 Human SwissProt: P20849 Human SwissProt: Q05722 Mouse SwissProt: P20850 Rat Unigene: 590892 Human Unigene: 154662 Mouse Unigene: 90726 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胶原蛋白9抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid