齿染色体开放阅读框6抗体
规格：1尘驳/1尘濒
英文名： CXorf6
别名： CG1; CXorf6; F18; Protein CG1; Chromosome X open reading frame 6.
分子量： 83kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CXorf6
交叉反应：Human, Mouse,
细胞定位：
齿染色体开放阅读框6抗体产物介绍：background: This gene encodes a mastermind-like domain containing protein. This protein may function as a transcriptional co-activator. Mutations in this gene are the cause of X-linked hypospadias type 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] Function: HypospadiasCXorf6 is a protein predicted based on an ORF found in chromosome 14 Preferentially expressed in skeletal muscle. Defects in CXorf6 are a cause of hypospadias. is a common malformation in which the urethra opens on the ventral side of the penis. It is considered a complex disorder with both genetic and environmental factors involved in the pathogenesis.齿染色体开放阅读框6抗体 Hypospadias can occur alone on an apparently multifactorial basis or as part of syndromes. Subcellular Location: Nucleus. Note=Punctate nuclear localization. Tissue Specificity: Expressed in fetal brain, fetal ovary and fetal testis. Expressed in brain, ovary, skin, testis, uterus. Highly expressed in skeletal muscle. DISEASE: Hypospadias 2, X-linked (HYSP2) [MIM:300758]: A common malformation in which the urethra opens on the ventral side of the penis, due to developmental arrest of urethral fusion. The opening can be located glandular, penile, or齿染色体开放阅读框6抗体 even more posterior in the scrotum or perineum. Hypospadias is a feature of several syndromic disorders, including the androgen insensitivity syndrome and Opitz syndrome. Note=The disease is caused by mutations affecting the gene represented in this entry. Gene ID: 10046 Database links: Entrez Gene: 10046 Human Omim: 300120 Human SwissProt: Q13495 Human Unigene: 20136 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
齿染色体开放阅读框6抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid