胆囊收缩素39抗体
规格：1尘驳/1尘濒
英文名： CCK39
别名： CCK; CCK39; Cholecystokinin 39; Cholecystokinin; CCKN_HUMAN.
分子量： 11kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCK39
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
胆囊收缩素39抗体产物介绍：background: Cholecystokinin is a brain/gut peptide. In the gut, it induces the release of pancreatic enzymes and the contraction of the gallbladder. In the brain, its physiologic role is unclear. The cholecystokinin pro-hormone is processed by endo- and exo-proteolytic cleavages. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010] Function: Cholecystokinin (CCK) is one of the most important hormone regulators of the digestive process. The peptide is concentrated in the proximal small intestine (CCK cells) and is secreted into the blood in response to the ingestion of proteins and fats, where its actions include the stimulation of pancreatic secretion, the modulation of insulin output, the regulation of gastric emptying, and gallbladder contraction. In the central 胆囊收缩素39抗体nervous system CCKergic fibres are widespread, being particularly abundant in the cerebral cortex. In some mesolimbic neurons projecting to the nucleus accumbens, CCK is colocalised with dopamine and it has been suggested that CCK might facilitate the function of dopamine in events such as stimulusreward associative behaviour. Secretion of CCK from the murine tumour cell line STC1 has been shown to be stimulated by pituitary adenylate cyclase activating protein (PACAP) and has raised the possibility that PACAP may function as a neuromodulator of CCK release from gut endocrine cells in vivo. Subunit: Binds to CCK-A receptors in the pancreas and CCK-B receptors in the brain (By similarity). Subcellular胆囊收缩素39抗体 Location: Secreted Post-translational modifications: The precursor is cleaved by proteases to produce a number of active cholecystokinins. Similarity: Belongs to the gastrin/cholecystokinin family. Gene ID: 885 Database links: Entrez Gene: 885 Human Entrez Gene: 12424 Mouse Entrez Gene: 397468 Pig Entrez Gene: 25298 Rat Omim: 118440 Human SwissProt: P06307 Human SwissProt: P09240 Mouse SwissProt: Q53WS9 Mouse SwissProt: Q8R041 Mouse SwissProt: Q9DCL5 Mouse SwissProt: P01356 Pig SwissProt: P01355 Rat Unigene: 458426 Human Unigene: 9781 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胆囊收缩素39抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid